Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22891945 | 0.83 | DGAT1 (0.34) | DGAT1MMP8CA1CA2CA7 | |
| SCHEMBL26996992 | 0.83 | DGAT1 (0.34) | DGAT1MMP8CA1CA2CA7 | |
| SCHEMBL16750132 | 0.78 | TSHR (0.38) | PIK3CDTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL12885564 | 0.77 | KISS1R (0.32) | DGAT1 | |
| SCHEMBL10257080 | 0.76 | ACACB (0.33) | CTSKCA1CA2 | |
| SCHEMBL10257384 | 0.76 | ACACB (0.33) | CTSKCA1CA2 | |
| SCHEMBL16417529 | 0.76 | ACACB (0.33) | CTSKCA1CA2 | |
| SCHEMBL806956 | 0.76 | DGAT1 (0.38) | DGAT1CA1CA7TSHRALDH1A1 | |
| SCHEMBL4069477 | 0.76 | DGAT1 (0.38) | DGAT1CA1CA7TSHRALDH1A1 | |
| SCHEMBL12600077 | 0.74 | DGAT1 (0.37) | DGAT1TSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977584-B | Compound for targeted ubiquitination degradation of PLK1 and BRD4 proteins and application thereof | JILIN UNIVERSITY (CN) | 2019-12-06 | — | — | CN | disclosed |