SCHEMBL2834520

SCHEMBL2834520

Brc1c2ccccc2c(-c2ccc(C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPK1 P28482 2/20 0.37
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ACHE P22303 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KIF11 P52732 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ESR1 P03372 2/20 0.31
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
GPR84 Q9NQS5 1/20 0.30
ESR2 Q92731 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2448770 0.85 TNKS (0.40) KIF11TNKSTNKS2GPR84
SCHEMBL12560663 0.83 MAPK1 (0.48) KDM4EL3MBTL1MAPK1MAPTTDP1
SCHEMBL3000291 0.83 KDM4E (0.42) KDM4EL3MBTL1MAPK1MAPTTDP1
SCHEMBL1534946 0.81 MAPK1 (0.50) KDM4EL3MBTL1MAPK1MAPTTDP1
SCHEMBL29603166 0.81 MAPK1 (0.50) KDM4EL3MBTL1MAPK1MAPTTDP1
SCHEMBL12560730 0.81 MAPK1 (0.50) KDM4EL3MBTL1MAPK1MAPTTDP1
SCHEMBL295397 0.81 MAPK1 (0.50) KDM4EL3MBTL1MAPK1MAPTTDP1
SCHEMBL30396122 0.81 MAPK1 (0.50) KDM4EL3MBTL1MAPK1MAPTTDP1
SCHEMBL4779228 0.81 KIF11 (0.52) KDM4EL3MBTL1MAPTCYP1A2CYP3A4
SCHEMBL13522772 0.80 ALDH1A1 (0.38) KDM4EMAPK1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1595292-B1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO LTD (KR) 2015-12-23 EP disclosed
US-7651787-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-01-26 US disclosed
US-7651787-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-01-26 US disclosed
US-7651787-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-01-26 US disclosed
CN-1751398-A Organic electroluminescent device LG ELECTRONICS INC (KR) 2006-03-22 CN disclosed
EP-1595292-A2 ORGANIC ELECTROLUMINESCENT DEVICE LG ELECTRONICS INC. (KR) 2005-11-16 EP disclosed
WO-2004075603-A2 ORGANIC ELECTROLUMINESCENT DEVICE LG ELECTRONICS INC. (KR) 2004-09-02 WO disclosed
US-20040161633-A1 Organic electroluminescent device LG ELECTRONICS INC. 2004-08-19 US disclosed