Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL29883666 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Tetradecylamine SCHEMBL8731499 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL29111186 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL9818042 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Dodecylamine SCHEMBL9551516 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL25341518 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL9444046 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL11504036 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL9614783 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Octadecylamine SCHEMBL11149028 | 0.98 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796347-B | Pendimethalin production process without nitric acid wastewater discharge | 江苏永安化工有限公司 | 2019-12-06 | — | — | CN | claimed |
| CN-115557477-A | Method for treating waste nitric acid by using microchannel reactor | 江苏永安化工有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-109796347-B | Pendimethalin production process without nitric acid wastewater discharge | 江苏永安化工有限公司 | 2019-12-06 | — | — | CN | disclosed |