Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.60 |
| ▸ | MMP2 | P08253 | 4/20 | 0.60 |
| ▸ | MMP9 | P14780 | 4/20 | 0.60 |
| ▸ | TGM2 | P21980 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40744 | 0.93 | TGM2 (0.68) | MMP1MMP2MMP9TGM2ALDH1A1 | |
| Ethylene SCHEMBL6400166 | 0.91 | TGM2 (0.66) | MMP1MMP2MMP9TGM2ALDH1A1 | |
| Dimethylamine SCHEMBL1263583 | 0.88 | TGM2 (0.62) | MMP1MMP2MMP9TGM2ALDH1A1 | |
| SCHEMBL124217 | 0.87 | TGM2 (0.71) | MMP1MMP2MMP9TGM2ALDH1A1 | |
| Acrylamide SCHEMBL28802284 | 0.86 | TGM2 (0.60) | MMP1MMP2MMP9TGM2ALDH1A1 | |
| SCHEMBL8838968 | 0.86 | TGM2 (0.60) | MMP1MMP2MMP9TGM2ALDH1A1 | |
| SCHEMBL1119154 | 0.85 | MMP1 (0.55) | MMP1MMP2MMP9TGM2ALDH1A1 | |
| Diethylamine SCHEMBL1263580 | 0.83 | TGM2 (0.57) | MMP1MMP2MMP9TGM2ALDH1A1 | |
| SCHEMBL11775423 | 0.83 | TGM2 (0.71) | MMP1MMP2MMP9TGM2ALDH1A1 | |
| Thiophene SCHEMBL28891798 | 0.83 | TGM2 (0.57) | MMP1MMP2MMP9TGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520128-A | Compositions and methods for treating complications and diseases associated with von Willebrand factor | BAND THERAPEUTICS LLC | 2019-11-29 | — | — | CN | disclosed |