Isothiocyanate

Isothiocyanate

SCHEMBL28345554

N=C=S.O=C(O)CN(CCN(CC(=O)O)C(Cc1ccccc1)C(=O)O)CC(=O)O.[Cd]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
CPA1 P15085 3/20 0.36
CPA3 P15088 3/20 0.36
CPB1 P15086 1/20 0.36
CPB2 Q96IY4 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
EYA2 O00167 1/20 0.35
APP P05067 1/20 0.35
ACE P12821 1/20 0.35
ALPI P09923 1/20 0.35
PKM P14618 1/20 0.35
PTGS1 P23219 1/20 0.35
XIAP P98170 1/20 0.35
SLC7A5 Q01650 1/20 0.35
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
CHRM2 P08172 1/20 0.34
ADRA2A P08913 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isothiocyanate SCHEMBL28348502 0.99 CYP1A2 (0.37) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL7596061 0.91 CYP1A2 (0.43) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL29588115 0.91 CYP1A2 (0.43) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL7668229 0.88 CYP1A2 (0.43) CYP1A2CPA1CPA3CPB1CPB2
Thiocyanic Acid SCHEMBL28131168 0.86 CYP1A2 (0.37) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL7597594 0.85 CYP1A2 (0.48) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL8398238 0.84 CYP1A2 (0.47) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL16312998 0.81 CYP1A2 (0.37) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL6135754 0.81 HSD17B10 (0.39) CYP1A2TDP1EYA2APPACE
SCHEMBL7598191 0.80 SLC7A5 (0.44) TDP1EYA2APPACESLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110684109-B Monoclonal antibody for identifying heavy metal cadmium and application thereof 武玉香 2021-07-09 CN claimed
CN-110684109-A Monoclonal antibody for identifying heavy metal cadmium and application thereof 武玉香 2020-01-14 CN claimed
CN-110684109-B Monoclonal antibody for identifying heavy metal cadmium and application thereof 武玉香 2021-07-09 CN disclosed
CN-110684109-A Monoclonal antibody for identifying heavy metal cadmium and application thereof 武玉香 2020-01-14 CN disclosed