Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600927 | 0.94 | SLC7A5 (0.49) | SLC7A5SLC6A2CA2CAMK2ANAALAD2 | |
| SCHEMBL29588115 | 0.88 | CYP1A2 (0.43) | SLC7A5TDP1EYA2APPACE | |
| SCHEMBL7596061 | 0.88 | CYP1A2 (0.43) | SLC7A5TDP1EYA2APPACE | |
| SCHEMBL7630147 | 0.88 | SLC7A5 (0.39) | SLC7A5CA2CA1CA4 | |
| SCHEMBL14357545 | 0.88 | SLC7A5 (0.51) | SLC7A5SLC6A2CA2CAMK2ANAALAD2 | |
| SCHEMBL9435308 | 0.87 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL5252487 | 0.87 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7668229 | 0.85 | CYP1A2 (0.43) | SLC7A5TDP1EYA2APPACE | |
| SCHEMBL9001972 | 0.83 | TDP1 (0.40) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7513236 | 0.83 | TDP1 (0.40) | TDP1EYA2APPACEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | claimed |
| JP-2002506049-A | — | — | 2002-02-26 | — | — | JP | claimed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | claimed |
| EP-1061956-A1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO S.p.A. (IT) | 2000-12-27 | — | — | EP | claimed |
| WO-1999045967-A1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO S.P.A. (IT) | 1999-09-16 | — | — | WO | claimed |
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | disclosed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | disclosed |
| EP-1061956-A1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO S.p.A. (IT) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999045967-A1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO S.P.A. (IT) | 1999-09-16 | — | — | WO | disclosed |