SCHEMBL7668229

SCHEMBL7668229

O=C(O)CN(CCN(CC(=O)O)[C@@H](Cc1ccccc1)C(=O)O)CCN(CC(=O)O)[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
CPA1 P15085 4/20 0.42
CPA3 P15088 3/20 0.42
CPB1 P15086 1/20 0.42
CPB2 Q96IY4 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
CHRM2 P08172 1/20 0.41
ADRA2A P08913 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
CYP2C19 P33261 1/20 0.41
ADRA1A P35348 1/20 0.41
DRD3 P35462 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596061 0.97 CYP1A2 (0.43) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL29588115 0.97 CYP1A2 (0.43) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL7597594 0.94 CYP1A2 (0.48) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL8398238 0.92 CYP1A2 (0.47) CYP1A2CPA1CPA3CPB1CPB2
Thiocyanic Acid SCHEMBL28131168 0.89 CYP1A2 (0.37) CYP1A2CPA1CPA3CPB1CPB2
Isothiocyanate SCHEMBL28348502 0.89 CYP1A2 (0.37) CYP1A2CPA1CPA3CPB1CPB2
Isothiocyanate SCHEMBL28345554 0.88 CYP1A2 (0.36) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL9468369 0.87 CYP1A2 (0.52) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL21864 0.87 CYP1A2 (0.52) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL6428029 0.86 LAP3 (0.43) CYP1A2CPA1CPA3CPB1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915829-A1 DIAGNOSTIC IMAGING CONTRAST AGENT WITH IMPROVED IN-SERUM-RELAXIVITY BRACCO S.p.A. (IT) 1999-05-19 EP claimed
WO-1998005625-A1 DIAGNOSTIC IMAGING CONTRAST AGENT WITH IMPROVED IN-SERUM-RELAXIVITY BRACCO S.P.A. (IT) 1998-02-12 WO claimed
US-6403055-B1 CARBOXYLATED POLYAMINE COMPOUND DIBRA S.P.A. (IT) 2002-06-11 US disclosed