Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763755 | 0.87 | TTR (0.46) | AURKAAURKBTTRCYP1A2CYP2D6 | |
| SCHEMBL28041867 | 0.86 | TTR (0.45) | AURKAAURKBTTRCYP1A2CYP2D6 | |
| SCHEMBL6747883 | 0.84 | ALDH1A1 (0.53) | AURKAAURKBCYP1A2CYP2D6MEN1 | |
| SCHEMBL2615797 | 0.83 | AURKA (0.44) | AURKAAURKBTTRCYP1A2CYP2D6 | |
| SCHEMBL4730731 | 0.81 | ALDH1A1 (0.43) | TTRCYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL7754466 | 0.81 | AURKA (0.42) | AURKAAURKBTTRCYP1A2PHLPP2 | |
| SCHEMBL14290611 | 0.80 | CYP1A2 (0.48) | AURKAAURKBTTRCYP1A2PHLPP2 | |
| SCHEMBL7831185 | 0.79 | TTR (0.45) | AURKAAURKBTTRCYP1A2CYP2D6 | |
| SCHEMBL7027692 | 0.79 | AURKA (0.53) | AURKAAURKBTTRCYP1A2PHLPP2 | |
| SCHEMBL2161129 | 0.78 | AURKA (0.49) | AURKAAURKBTTRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521808-B1 | COMPOSITIONS AND INKS CONTAINING DISAZO DYES | FUJIFILM IMAGING COLORANTS LTD (GB) | 2012-08-01 | — | — | EP | disclosed |
| US-4460505-A | Dyestuffs, processes for their preparation and their use for dyeing materials containing hydroxyl groups or nitrogen | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0012350-B1 | AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN THE DYEING OF N-CONTAINING MATERIALS | BAYER AG (DE) | 1982-04-07 | — | — | EP | disclosed |