Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17866621 | 0.86 | AGTR1 (0.60) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL18732402 | 0.85 | MEN1 (0.89) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL3631391 | 0.85 | MEN1 (0.89) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL58442 | 0.85 | MEN1 (1.00) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL13203474 | 0.84 | MCL1 (0.61) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL16077969 | 0.83 | MEN1 (0.94) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| Bromide SCHEMBL10753629 | 0.83 | MEN1 (0.94) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL4406097 | 0.83 | MEN1 (0.94) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL5945940 | 0.83 | MEN1 (0.94) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL22042815 | 0.83 | MCL1 (0.70) | RAB9AMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642779-B | 2, 6-diaryl pyridine substance and preparation method thereof | 温州大学 | 2021-04-16 | — | — | CN | disclosed |
| CN-110642779-A | 2, 6-diaryl pyridine substance and preparation method thereof | 温州大学 | 2020-01-03 | — | — | CN | disclosed |