Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 11/20 | 0.59 |
| ▸ | TTBK2 | Q6IQ55 | 11/20 | 0.59 |
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12709725 | 1.00 | TTBK1 (0.59) | TTBK1TTBK2HPGDSPDPK1MKNK1 | |
| Hydrochloric Acid SCHEMBL29754738 | 0.98 | TTBK1 (0.57) | TTBK1TTBK2HPGDSPDPK1 | |
| SCHEMBL3165812 | 0.82 | TTBK1 (0.61) | TTBK1TTBK2HPGDSMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL13736720 | 0.80 | TTBK1 (0.59) | TTBK1TTBK2HPGDSMKNK1MKNK2 | |
| SCHEMBL23619521 | 0.80 | TTBK1 (0.59) | TTBK1TTBK2HPGDSMKNK1MKNK2 | |
| SCHEMBL1815838 | 0.79 | HPGDS (0.55) | TTBK1TTBK2HPGDS | |
| SCHEMBL22508755 | 0.79 | TTBK1 (0.59) | TTBK1TTBK2HPGDSMKNK1MKNK2 | |
| SCHEMBL23409028 | 0.79 | TTBK1 (0.59) | TTBK1TTBK2HPGDS | |
| Hydrochloric Acid SCHEMBL29729076 | 0.78 | TTBK1 (0.58) | TTBK1TTBK2HPGDS | |
| SCHEMBL16266363 | 0.77 | TTBK1 (0.61) | TTBK1TTBK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822112-B | Preparation method of tofacitinib compound | 山东罗欣药业集团恒欣药业有限公司 | 2019-12-20 | — | — | CN | disclosed |