Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MECP2 | P51608 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28346359 | 0.97 | NOTUM (0.49) | NOTUMALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL28349908 | 0.88 | KDM4E (0.55) | NOTUMALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL28349898 | 0.77 | KDM4E (0.52) | NOTUMALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL28349757 | 0.76 | ALDH1A1 (0.43) | NOTUMALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL28346365 | 0.76 | NOTUM (0.49) | NOTUMALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL28349907 | 0.76 | PTGER4 (0.57) | ALDH1A1KMT2AHPGDMEN1MAPT | |
| SCHEMBL28346327 | 0.74 | MAPT (0.53) | ALDH1A1KMT2AHPGDMEN1MAPT | |
| SCHEMBL31711447 | 0.74 | CYP2A6 (0.53) | ALDH1A1KMT2AHPGDMEN1MAPT | |
| SCHEMBL2713434 | 0.74 | CYP2A6 (0.53) | ALDH1A1KMT2AHPGDMEN1MAPT | |
| SCHEMBL28349178 | 0.73 | NOTUM (0.46) | NOTUMALDH1A1KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627783-B | Preparation method of Schiff base containing carbazolyl and oxadiazolyl or thiadiazolyl | 陕西科技大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-110627783-A | Preparation method of Schiff base containing carbazolyl and oxadiazolyl or thiadiazolyl | 陕西科技大学 | 2019-12-31 | — | — | CN | disclosed |