Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28346334 | 0.88 | NOTUM (0.52) | KDM4ENOTUMPTGER4NPC1RAB9A | |
| SCHEMBL28346359 | 0.85 | NOTUM (0.49) | KDM4ENOTUMPTGER4NPC1RAB9A | |
| SCHEMBL28349898 | 0.78 | KDM4E (0.52) | KDM4ENOTUMPTGER4NPC1RAB9A | |
| SCHEMBL1143348 | 0.74 | KDM4E (1.00) | KDM4ENOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL2713434 | 0.72 | CYP2A6 (0.53) | KDM4EPTGER4RAB9AALDH1A1MAPT | |
| SCHEMBL31711447 | 0.72 | CYP2A6 (0.53) | KDM4EPTGER4RAB9AALDH1A1MAPT | |
| SCHEMBL28349907 | 0.72 | PTGER4 (0.57) | KDM4EPTGER4RAB9AALDH1A1MAPT | |
| SCHEMBL28346327 | 0.70 | MAPT (0.53) | KDM4EPTGER4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28346892 | 0.70 | KDM4E (0.55) | KDM4ENOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL718797 | 0.66 | PTGER4 (0.64) | KDM4EPTGER4RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627783-B | Preparation method of Schiff base containing carbazolyl and oxadiazolyl or thiadiazolyl | 陕西科技大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-110627783-A | Preparation method of Schiff base containing carbazolyl and oxadiazolyl or thiadiazolyl | 陕西科技大学 | 2019-12-31 | — | — | CN | disclosed |