Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 9/20 | 0.34 |
| ▸ | PPARD | Q03181 | 9/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214039 | 0.92 | CA12 (0.32) | PPARAPPARDPPARGALDH1A1KDM4E | |
| SCHEMBL21542468 | 0.92 | CA12 (0.32) | PPARAPPARDPPARGALDH1A1KDM4E | |
| SCHEMBL29231402 | 0.85 | PPARD (0.35) | PTGER1PPARAPPARDPPARGFFAR1 | |
| SCHEMBL28344327 | 0.83 | ALDH1A1 (0.37) | PTGER1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30829491 | 0.79 | PPARD (0.33) | PPARAPPARDPPARGALDH1A1KDM4E | |
| SCHEMBL21542457 | 0.79 | KDM4E (0.33) | PTGER1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20214017 | 0.79 | KDM4E (0.33) | PTGER1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28343823 | 0.76 | PTGER1 (0.38) | PTGER1PPARAPPARDPPARGALDH1A1 | |
| SCHEMBL20213964 | 0.76 | ALDH1A1 (0.34) | PTGER1PPARDALDH1A1KDM4EMEN1 | |
| SCHEMBL20213979 | 0.73 | ALDH1A1 (0.38) | PTGER1PPARDALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603254-A | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2019-12-20 | — | — | CN | disclosed |