Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29231402 | 0.93 | PPARD (0.35) | PPARDENPP2PPARAPPARGFFAR1 | |
| SCHEMBL21542468 | 0.86 | CA12 (0.32) | PPARDNPC1ALDH1A1GAAENPP2 | |
| SCHEMBL20214039 | 0.86 | CA12 (0.32) | PPARDNPC1ALDH1A1GAAENPP2 | |
| SCHEMBL28346707 | 0.79 | PTGER1 (0.34) | PPARDNPC1ALDH1A1GAAENPP2 | |
| SCHEMBL20214017 | 0.73 | KDM4E (0.33) | ALDH1A1GAADHODHKDM4EMEN1 | |
| SCHEMBL20213964 | 0.70 | ALDH1A1 (0.34) | PPARDNPC1ALDH1A1GAADHODH | |
| SCHEMBL20213979 | 0.69 | ALDH1A1 (0.38) | PPARDNPC1ALDH1A1GAADHODH | |
| SCHEMBL20214002 | 0.65 | ALDH1A1 (0.35) | PPARDNPC1ALDH1A1GAADHODH | |
| SCHEMBL2362965 | 0.64 | SCN9A (0.45) | ALDH1A1GAAKDM4EMEN1MAPT | |
| SCHEMBL29231533 | 0.63 | XPO1 (0.39) | DHODHPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603254-B | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-04-12 | — | — | CN | disclosed |