SCHEMBL283472

SCHEMBL283472

CCOC(=O)Nc1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
HPGD P15428 1/20 1.00
KDM4E B2RXH2 5/20 0.63
POLB P06746 2/20 0.63
CDC25B P30305 2/20 0.61
CDC25A P30304 1/20 0.61
CDC25C P30307 1/20 0.61
EPHX1 P07099 1/20 0.57
GLA P06280 1/20 0.57
GAA P10253 1/20 0.57
LMNA P02545 1/20 0.56
KMT2A Q03164 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C19 P33261 2/20 0.56
MAOB P27338 1/20 0.55
MAPT P10636 1/20 0.54
RAB9A P51151 2/20 0.54
NPC1 O15118 1/20 0.53
CYP3A4 P08684 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9443224 0.93 ALDH1A1 (0.86) ALDH1A1HPGDKDM4EPOLBCDC25B
Acrylic Acid SCHEMBL17822133 0.90 ALDH1A1 (0.82) ALDH1A1HPGDKDM4EPOLBCDC25B
SCHEMBL7916743 0.90 ALDH1A1 (0.81) ALDH1A1HPGDKDM4EPOLBCDC25B
SCHEMBL20702693 0.90 ALDH1A1 (0.81) ALDH1A1HPGDKDM4EPOLBCDC25B
SCHEMBL10959203 0.88 HPGD (0.78) ALDH1A1HPGDKDM4EPOLBCDC25B
SCHEMBL11766437 0.87 ALDH1A1 (0.77) ALDH1A1HPGDKDM4EPOLBGLA
SCHEMBL11340283 0.86 HPGD (0.76) ALDH1A1HPGDKDM4EPOLBGLA
SCHEMBL11656966 0.86 ALDH1A1 (0.76) ALDH1A1HPGDKDM4EPOLBGLA
SCHEMBL9813594 0.85 ALDH1A1 (0.74) ALDH1A1HPGDKDM4EPOLBEPHX1
SCHEMBL9398072 0.84 ALDH1A1 (0.73) ALDH1A1HPGDKDM4EPOLBCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3661921-B1 SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME NODTHERA LTD (GB) 2023-10-18 EP disclosed
CN-111315800-B Triazine ring-containing polymer and composition comprising same 日产化学株式会社 2022-05-31 CN disclosed
CN-107849425-B Solvent-free photocurable adhesive composition 日产化学工业株式会社 2021-09-21 CN disclosed
CN-107849392-B Film-forming composition for inkjet coating 日产化学工业株式会社 2021-07-13 CN disclosed
US-20210179779-A1 TRIAZINE-RING-CONTAINING POLYMER AND COMPOSITION INCLUDING SAME NISSAN CHEMICAL CORPORATION (JP) 2021-06-17 US disclosed
CN-108602953-B Triazine ring-containing polymer and film-forming composition containing the same 日产化学工业株式会社 2021-02-05 CN disclosed
CN-111315800-A Triazine ring-containing polymer and composition comprising same 日产化学株式会社 2020-06-19 CN disclosed
US-10619073-B2 Film-forming composition for ink-jet coating NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-04-14 US disclosed
US-10604681-B2 Solvent-free light-curable adhesive composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-03-31 US disclosed
CN-107580607-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2019-09-27 CN disclosed
EP-2628769-A1 FILM-FORMING COMPOSITION Nissan Chemical Industries, Ltd. (JP) 2013-08-21 EP disclosed
EP-2610280-A1 TRIAZINE RING-CONTAINING POLYMER AND MEMBRANE-FORMING COMPOSITION CONTAINING THE SAME Nissan Chemical Industries, Ltd. (JP) 2013-07-03 EP disclosed
US-20130154043-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-06-20 US disclosed
CN-102498095-A Indoline derivatives TOKYO INST TECH 2012-06-13 CN disclosed
EP-1888615-B1 17 -HSD1 AND STS INHIBITORS ABBOTT PRODUCTS GMBH (DE) 2012-05-16 EP disclosed
EP-2428529-A1 TRIAZINE RING-CONTAINING POLYMER AND FILM-FORMING COMPOSITION COMPRISING SAME Nissan Chemical Industries, Ltd. (JP) 2012-03-14 EP disclosed
US-20120049308-A1 TRIAZINE RING-CONTAINING POLYMER AND FILM-FORMING COMPOSITION COMPRISING SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-01 US disclosed
US-20040077821-A1 Flame retarding resin composition CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US disclosed
CN-1257482-A Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist GLAXO WELLCOME SPA (IT) 2000-06-21 CN disclosed
US-3962302-A Production of isocyanates from esters of carbamic acids (urethanes) ATLANTIC RICHFIELD COMPANY (US) 1976-06-08 US disclosed