Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916743 | 0.93 | ALDH1A1 (0.81) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28401182 | 0.86 | ALDH1A1 (0.72) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL283472 | 0.86 | ALDH1A1 (1.00) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12266506 | 0.86 | ALDH1A1 (0.72) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11659539 | 0.85 | ALDH1A1 (0.65) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29209712 | 0.84 | ALDH1A1 (0.68) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11765835 | 0.83 | KDM4E (0.76) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10447849 | 0.82 | ALDH1A1 (0.71) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL69360 | 0.81 | NPC1 (0.71) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30593915 | 0.81 | NPC1 (0.71) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4290970-A | Process for the manufacture of aromatic di- and/or polyisocyanates | BASF AKTIENGESELLSCHAFT (DE) | 1981-09-22 | — | — | US | disclosed |