Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28351028 | 0.89 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDKMT2ANPC1MEN1 | |
| SCHEMBL28351003 | 0.86 | KMT2A (0.65) | SMN1; SMN2HPGDKMT2AMEN1RAB9A | |
| SCHEMBL28347347 | 0.86 | KMT2A (0.60) | SMN1; SMN2HPGDKMT2ANPC1MEN1 | |
| SCHEMBL28350833 | 0.86 | ALDH1A1 (0.58) | SMN1; SMN2HPGDKMT2ANPC1MEN1 | |
| SCHEMBL28350767 | 0.83 | USP2 (0.52) | KMT2ANPC1MEN1RAB9ALMNA | |
| SCHEMBL28360908 | 0.81 | KMT2A (0.47) | SMN1; SMN2HPGDKMT2ANPC1MEN1 | |
| SCHEMBL28347340 | 0.81 | KMT2A (0.54) | SMN1; SMN2MAPK1KMT2AMEN1LMNA | |
| SCHEMBL28347712 | 0.81 | KMT2A (0.58) | SMN1; SMN2KMT2ANPC1MEN1RAB9A | |
| SCHEMBL28347339 | 0.81 | NPC1 (0.55) | SMN1; SMN2HPGDNPC1RAB9ALMNA | |
| SCHEMBL28347418 | 0.80 | CASP3 (0.56) | SMN1; SMN2HPGDKMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698394-B | 2- (2-chloronicotinamido) ethyl benzoate derivative and preparation method and application thereof | 浙江工业大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-110698394-A | 2- (2-chloronicotinamido) ethyl benzoate derivative and preparation method and application thereof | 浙江工业大学 | 2020-01-17 | — | — | CN | disclosed |