Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25191166 | 0.97 | CES2 (0.38) | CES2CES1RAB9APTPN5MEN1 | |
| SCHEMBL2475808 | 0.89 | CES2 (0.48) | CES2CES1RAB9APTPN5MEN1 | |
| SCHEMBL223266 | 0.85 | SRC (0.54) | RAB9APTPN5MEN1KMT2ALMNA | |
| SCHEMBL4103871 | 0.84 | SRC (0.50) | CES2CES1MEN1KMT2ABLM | |
| SCHEMBL11401703 | 0.84 | CYP3A4 (0.41) | RAB9APTPN5MEN1KMT2ALMNA | |
| SCHEMBL28681455 | 0.84 | RAB9A (0.44) | CES2CES1RAB9APTPN5MEN1 | |
| SCHEMBL27342545 | 0.83 | SRC (0.52) | RAB9APTPN5MEN1KMT2ALMNA | |
| SCHEMBL223469 | 0.82 | SRC (0.52) | CES2CES1RAB9APTPN5MEN1 | |
| SCHEMBL28669526 | 0.82 | POLB (0.41) | CES2CES1RAB9APTPN5MEN1 | |
| SCHEMBL28681444 | 0.81 | CES2 (0.42) | CES2CES1RAB9APTPN5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107286300-B | Polyorganosiloxane-containing graft copolymer, resin composition, and molded article | 三菱化学株式会社 | 2021-09-28 | — | — | CN | disclosed |
| CN-104755516-B | Polyorganosiloxane-containing graft copolymer, resin composition, and molded article | 三菱化学株式会社 | 2020-01-24 | — | — | CN | disclosed |