SCHEMBL28347983

SCHEMBL28347983

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)NCC(=O)NCCCCNCCCN

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 2/20 0.50
CASP2 P42575 1/20 0.45
NAAA Q02083 1/20 0.43
PAOX Q6QHF9 1/20 0.43
RELA Q04206 4/20 0.43
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
DNM1 Q05193 1/20 0.42
GRIA1 P42261 1/20 0.42
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
RRM1 P23921 1/20 0.41
KDM4A O75164 1/20 0.41
HIF1A Q16665 1/20 0.41
TET2 Q6N021 1/20 0.41
DOHH Q9BU89 1/20 0.41
EPHX1 P07099 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30997315 1.00 SLC6A5 (0.50) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL3820683 0.99 SLC6A5 (0.49) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL28817375 0.86 SLC6A5 (0.47) SLC6A5CASP2NAAAPAOXRELA
Spermine SCHEMBL7044349 0.86 PAOX (0.45) SLC6A5CASP2PAOXRELAGNAI3
SCHEMBL27817058 0.85 SLC6A5 (0.46) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL27490298 0.85 SLC6A5 (0.46) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL27509598 0.84 SLC6A5 (0.56) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL27771211 0.84 SLC6A5 (0.56) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL19412267 0.83 SLC6A5 (0.47) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL3394523 0.81 SLC6A5 (0.47) SLC6A5CASP2NAAAPAOXRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114206463-B Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2024-06-11 CN disclosed
CN-118043306-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2024-05-14 CN disclosed
CN-114391008-B Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2024-05-03 CN disclosed
CN-117771213-A Lipid nanoparticle compositions and uses thereof 北京剂泰医药科技有限公司 2024-03-29 CN disclosed
CN-117580587-A Coronavirus nucleic acid vaccine based on sequences derived from SARS-CoV-2 Omikovia strain 苏州艾博生物科技有限公司 2024-02-20 CN disclosed
CN-117202895-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-12-08 CN disclosed
CN-117069785-A Lipid compounds and lipid nanoparticle compositions 中生复诺健生物科技(上海)有限公司 2023-11-17 CN disclosed
CN-117083291-A Coronavirus nucleic acid vaccine based on sequences derived from SARS-CoV-2Delta strain 苏州艾博生物科技有限公司 2023-11-17 CN disclosed
CN-117043343-A Nucleic acid vaccine for mutant coronaviruses 苏州艾博生物科技有限公司 2023-11-10 CN disclosed
CN-117003658-A Lipid Nanoparticle Compositions 苏州艾博生物科技有限公司 2023-11-07 CN disclosed
CN-116940685-A Coronavirus multivalent nucleic acid vaccine based on sequences derived from SARS-CoV-2Beta and Delta strains 苏州艾博生物科技有限公司 2023-10-24 CN disclosed
CN-116829578-A Polynucleotides encoding interleukin-12 (IL-12) and compositions and methods related thereto 苏州艾博生物科技有限公司 2023-09-29 CN disclosed
CN-116472275-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-07-21 CN disclosed
CN-116323627-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-06-23 CN disclosed
CN-114206827-B Lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-05-23 CN disclosed
CN-112567032-A Methods and compositions for genome editing 利甘达尔股份有限公司 2021-03-26 CN disclosed
CN-112543650-A Methods and compositions for genome editing 利甘达尔股份有限公司 2021-03-23 CN disclosed
CN-110582302-A Compositions and methods for nucleic acid and/or protein payload delivery 利甘达尔股份有限公司 2019-12-17 CN disclosed