SCHEMBL28817375

SCHEMBL28817375

CCCCCCCCCCCCCCCCCN(CC(=O)NCCCCNCCCN)NCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 2/20 0.47
CASP2 P42575 1/20 0.45
NAAA Q02083 1/20 0.43
PAOX Q6QHF9 1/20 0.43
RELA Q04206 4/20 0.43
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
DNM1 Q05193 1/20 0.42
GRIA1 P42261 1/20 0.42
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
RRM1 P23921 1/20 0.41
KDM4A O75164 1/20 0.41
HIF1A Q16665 1/20 0.41
TET2 Q6N021 1/20 0.41
DOHH Q9BU89 1/20 0.41
EPHX1 P07099 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27490298 0.99 SLC6A5 (0.46) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL27817058 0.99 SLC6A5 (0.46) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL30997315 0.86 SLC6A5 (0.50) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL1037232 0.86 SLC6A5 (0.47) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL28093185 0.86 SLC6A5 (0.47) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL31095863 0.86 SLC6A5 (0.47) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL3394523 0.86 SLC6A5 (0.47) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL28347983 0.86 SLC6A5 (0.50) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL27971595 0.85 SLC6A5 (0.46) SLC6A5CASP2NAAAPAOXRELA
SCHEMBL28264890 0.85 SLC6A5 (0.46) SLC6A5CASP2NAAAPAOXRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104870022-A In vivo production of proteins modeRNA Therapeutics 2015-08-26 CN disclosed
CN-104411338-A Modified polynucleotides for production of biologics and proteins associated with human diseases modeRNA Therapeutics 2015-03-11 CN disclosed