Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348024 | 0.82 | LTA4H (0.62) | LTA4HCYP17A1CYP11B1CYP11B2PRMT6 | |
| SCHEMBL27594388 | 0.79 | LTA4H (0.58) | LTA4HCYP17A1CYP11B1CYP11B2PRMT6 | |
| SCHEMBL3245398 | 0.76 | LTA4H (0.63) | LTA4HCYP17A1CYP11B1CYP11B2PRMT6 | |
| SCHEMBL28347614 | 0.76 | MAOB (0.52) | KCNH2HPGDSMN1; SMN2FFAR1MAOB | |
| SCHEMBL11990244 | 0.76 | LTA4H (0.63) | LTA4HCYP17A1CYP11B1CYP11B2PRMT6 | |
| SCHEMBL404521 | 0.76 | LTA4H (0.68) | LTA4HCYP17A1CYP11B1CYP11B2PRMT6 | |
| SCHEMBL10564184 | 0.75 | LTA4H (0.61) | LTA4HCYP17A1CYP11B1CYP11B2PRMT6 | |
| SCHEMBL4316723 | 0.74 | LTA4H (0.56) | LTA4HCYP17A1CYP11B1CYP11B2PRMT6 | |
| SCHEMBL10594132 | 0.73 | TAAR1 (0.39) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5828519 | 0.72 | LTA4H (0.68) | LTA4HCYP17A1CYP11B1CYP11B2PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563535-B | Method for synthesizing 1, 2-disubstituted olefin compound by alkyne alkylation | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-110563535-A | method for synthesizing 1, 2-disubstituted olefin compound by alkyne alkylation | 浙江工业大学 | 2019-12-13 | — | — | CN | disclosed |