SCHEMBL28348121

SCHEMBL28348121

Brc1sc2cc(-c3cccc4ccccc34)ccc2c1Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.39
ACMSD Q8TDX5 1/20 0.39
PPARG P37231 9/20 0.37
PPARA Q07869 9/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PPARD Q03181 1/20 0.37
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
EDNRB P24530 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28882472 0.82 LIMK1 (0.40) MCL1KDM4EGLAMAPTKMT2A
SCHEMBL28348129 0.77 MAPT (0.44) MCL1KDM4EGLAMAPTKMT2A
SCHEMBL31442400 0.77 MCL1 (0.47) MCL1ACMSDKDM4EMAPTHDAC8
SCHEMBL28351539 0.77 S1PR5 (0.38) HDAC8
SCHEMBL28348700 0.75 MCL1 (0.40) MCL1ACMSDPPARGPPARACYP2C9
SCHEMBL24363254 0.75 MCL1 (0.41) MCL1ACMSDMAPTHDAC8HDAC6
SCHEMBL28348158 0.74 ESR1 (0.38) MAPT
SCHEMBL30257656 0.74 MCL1 (0.45) MCL1ACMSDKDM4EHDAC8HDAC6
SCHEMBL18429704 0.74 MCL1 (0.45) MCL1ACMSDKDM4EHDAC8HDAC6
SCHEMBL28352094 0.72 ENPP3 (0.41) CYP2C9CYP2C19KDM4EGLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734452-A semiconductor materials, and preparation method and application thereof 北京大学深圳研究生院 2020-01-31 CN disclosed