SCHEMBL28348129

SCHEMBL28348129

Brc1sc2ccccc2c1Oc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 2/20 0.44
GLA P06280 1/20 0.44
GPR3 P46089 1/20 0.41
LTA4H P09960 4/20 0.39
TSHR P16473 1/20 0.39
KDM1A O60341 1/20 0.35
TDP1 Q9NUW8 3/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CXCR2 P25025 1/20 0.35
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28352094 0.83 ENPP3 (0.41) MAPTKMT2AKDM4EGLAGPR3
SCHEMBL28882472 0.82 LIMK1 (0.40) MAPTKMT2AKDM4EGLATDP1
SCHEMBL28348121 0.77 MCL1 (0.39) MAPTKMT2AKDM4EGLAMCL1
SCHEMBL25383926 0.77 ALDH1A1 (0.48) MAPTKMT2AKDM4EGLAGPR3
SCHEMBL30557573 0.77 ALDH1A1 (0.48) MAPTKMT2AKDM4EGLAGPR3
SCHEMBL6440449 0.76 ESR1 (0.48) MAPTKMT2AKDM4EGLAGPR3
SCHEMBL28351705 0.76 CNR2 (0.41) KMT2AKDM4ETP53SMN1; SMN2MEN1
SCHEMBL28352092 0.76 MCL1 (0.41) MAPTKDM4EGPR3TDP1L3MBTL1
SCHEMBL4898172 0.70 KDM4E (0.70) MAPTKMT2AKDM4EGLALTA4H
SCHEMBL30003990 0.70 KDM4E (0.70) MAPTKMT2AKDM4EGLALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734451-B Semiconductor material, preparation method thereof and organic light-emitting diode 北京大学深圳研究生院 2022-07-22 CN disclosed
CN-110734452-A semiconductor materials, and preparation method and application thereof 北京大学深圳研究生院 2020-01-31 CN disclosed
CN-110734453-A amine derivatives, preparation method thereof and organic light emitting diode 北京大学深圳研究生院 2020-01-31 CN disclosed
CN-110734451-A semiconductor materials, preparation method thereof and organic light emitting diode 北京大学深圳研究生院 2020-01-31 CN disclosed