SCHEMBL28348198

SCHEMBL28348198

ON=C(c1ccccc1)c1ccc(O)cc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.66
CYP3A4 P08684 1/20 0.66
CYP2D6 P10635 1/20 0.66
ESR2 Q92731 11/20 0.63
ESR1 P03372 10/20 0.63
MGLL Q99685 3/20 0.61
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
GAA P10253 2/20 0.58
USP2 O75604 1/20 0.58
KEAP1 Q14145 1/20 0.58
NFE2L2 Q16236 1/20 0.58
CA12 O43570 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
TSHR P16473 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17988306 1.00 CYP1A2 (0.66) CYP1A2CYP3A4CYP2D6ESR2ESR1
SCHEMBL6374648 0.89 ESR2 (0.68) CYP1A2CYP3A4CYP2D6ESR2ESR1
SCHEMBL6374651 0.89 ESR2 (0.68) CYP1A2CYP3A4CYP2D6ESR2ESR1
SCHEMBL14765216 0.82 MGLL (0.50) CYP1A2CYP3A4CYP2D6ESR2ESR1
SCHEMBL13006110 0.82 CYP1A2 (0.62) CYP1A2CYP3A4CYP2D6ESR2ESR1
SCHEMBL13005901 0.82 CYP1A2 (0.62) CYP1A2CYP3A4CYP2D6ESR2ESR1
SCHEMBL4746337 0.82 ESR2 (0.69) CYP1A2CYP3A4CYP2D6ESR2ESR1
SCHEMBL4746340 0.82 ESR2 (0.69) CYP1A2CYP3A4CYP2D6ESR2ESR1
SCHEMBL13006105 0.82 ESR2 (0.70) CYP1A2CYP3A4CYP2D6ESR2ESR1
SCHEMBL24451314 0.82 MGLL (0.66) CYP1A2CYP3A4CYP2D6ESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110714213-A Cyanide-free alkaline cuprous copper electroplating complexing agent 武汉奥邦表面技术有限公司 2020-01-21 CN claimed