Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834662 | 1.00 | CES2 (0.61) | CES2NAAAHTTMEN1THRB | |
| SCHEMBL15273140 | 0.83 | CES2 (0.61) | CES2NAAAHTTMEN1THRB | |
| SCHEMBL29024703 | 0.79 | NAAA (0.58) | CES2NAAAHTTMEN1THRB | |
| SCHEMBL5224434 | 0.79 | NAAA (0.58) | CES2NAAAHTTMEN1THRB | |
| SCHEMBL29024706 | 0.79 | NAAA (0.58) | CES2NAAAHTTMEN1THRB | |
| SCHEMBL8466858 | 0.79 | CES2 (0.68) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL2766744 | 0.79 | CES2 (0.68) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL8092040 | 0.77 | CES2 (0.65) | CES2NAAAHTTMEN1THRB | |
| SCHEMBL8469575 | 0.77 | CES2 (0.65) | CES2NAAAHTTMEN1THRB | |
| SCHEMBL7455105 | 0.77 | CES2 (0.65) | CES2NAAAHTTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112567032-A | Methods and compositions for genome editing | 利甘达尔股份有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112543650-A | Methods and compositions for genome editing | 利甘达尔股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-110582302-A | Compositions and methods for nucleic acid and/or protein payload delivery | 利甘达尔股份有限公司 | 2019-12-17 | — | — | CN | disclosed |