SCHEMBL28348382

SCHEMBL28348382

NCC(=O)C(CO)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 2/20 0.40
GLRA1 P23415 1/20 0.40
SLC6A9 P48067 1/20 0.40
SLC1A1 P43005 1/20 0.36
ALDH1A1 P00352 1/20 0.34
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
GABRR1 P24046 3/20 0.33
TGFBR1 P36897 1/20 0.33
ENPEP Q07075 2/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
PDE4A P27815 1/20 0.32
GSR P00390 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC7A11 Q9UPY5 1/20 0.31
RNPEP Q9H4A4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7532120 0.76 GLRA1 (0.45) OR51E2GLRA1SLC6A9ALDH1A1GABRR1
SCHEMBL8125795 0.76 GABRR1 (0.48) OR51E2GLRA1SLC6A9SLC1A1ALDH1A1
SCHEMBL828874 0.75
SCHEMBL126424 0.72 LDHA (0.42) OR51E2SLC1A1USP2SLCO1B1TGFBR1
SCHEMBL364679 0.72 OR51E2 (0.39) OR51E2SLC1A1USP2SLCO1B1ENPEP
SCHEMBL27566415 0.72 GLRA1 (0.35) OR51E2GLRA1SLC6A9ALDH1A1GABRR1
SCHEMBL31317974 0.71 OR51E2 (0.44) OR51E2GLRA1SLC6A9SLC1A1ALDH1A1
SCHEMBL28839419 0.71 OR51E2 (0.44) OR51E2GLRA1SLC6A9SLC1A1ALDH1A1
SCHEMBL8519056 0.70 GSR (0.56) ALDH1A1GABRR1TSHRGSRRNPEP
SCHEMBL7436381 0.69 GSR (0.54) ALDH1A1GSRRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110642873-A Method for preparing aspoxicillin 黄焕军 2020-01-03 CN disclosed