Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11872543 | 0.78 | TDP1 (0.46) | LDHASRRFOLH1TDP1TSHR | |
| SCHEMBL7684983 | 0.76 | LDHA (0.40) | LDHASRRFOLH1TDP1TSHR | |
| SCHEMBL828874 | 0.75 | — | — | |
| SCHEMBL26668830 | 0.74 | FOLH1 (0.58) | FOLH1SLC1A1RIMKLANAALAD2 | |
| SCHEMBL28348382 | 0.72 | OR51E2 (0.40) | OR51E2TGFBR1CYP2C9TSHRPDE4A | |
| SCHEMBL364679 | 0.72 | OR51E2 (0.39) | OR51E2CYP2C9TSHRPDE4ASLC1A1 | |
| SCHEMBL3788183 | 0.72 | OR51E2 (0.52) | LDHASRROR51E2CYP2C9TSHR | |
| SCHEMBL5143583 | 0.72 | RNPEP (0.44) | FOLH1 | |
| SCHEMBL7077910 | 0.71 | LDHA (0.47) | LDHASRROR51E2FOLH1TDP1 | |
| SCHEMBL11307455 | 0.70 | GRIK1 (0.39) | LDHASRRFOLH1CYP2C9SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9719079-B2 | Aldolases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2017-08-01 | — | — | US | disclosed |
| EP-3153580-A2 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BASF Enzymes LLC (US) | 2017-04-12 | — | — | EP | disclosed |
| US-9518280-B2 | Aldolases, nucleic acids encoding them and methods for making and using them | CARGILL, INCORPORATED (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2385108-B1 | Aldolases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20160251643-A1 | Aldolases, Nucleic Acids Encoding Them and Methods for Making and Using Them | VERENIUM CORPORATION | 2016-09-01 | — | — | US | disclosed |
| US-9290755-B2 | Aldolases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150111260-A1 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | CARGILL, INCORPORATED | 2015-04-23 | — | — | US | disclosed |
| US-9005938-B2 | Aldolases, nucleic acids encoding them and methods for making and using them | CARGILL, INCORPORATED (US) | 2015-04-14 | — | — | US | disclosed |
| EP-2322643-B1 | Aldolases, nucleic acids encoding them and methods for making and using them | CARGILL INC (US) | 2014-07-09 | — | — | EP | disclosed |
| EP-2316962-B1 | Aldolases, nucleic acids encoding them and methods for making and using them | CARGILL INC (US) | 2014-07-09 | — | — | EP | disclosed |
| US-20100095390-A1 | Aldolases, Nucleic Acids Encoding Them and Methods for Making and Using Them | VERENIUM CORPORATION | 2010-04-15 | — | — | US | disclosed |
| EP-2112227-A1 | Aldolases, nucleic acids encoding them and methods for making and using them | Cargill, Incorporated (US) | 2009-10-28 | — | — | EP | disclosed |
| EP-1999256-A4 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORP (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1999256-A2 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | Verenium Corporation (US) | 2008-12-10 | — | — | EP | disclosed |
| EP-1994161-A2 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | CARGILL, INCORPORATED (US) | 2008-11-26 | — | — | EP | disclosed |
| US-20080020435-A1 | Aldolases, nucleic acids encoding them and methods for making and using them | CARGILL, INCORPORATED (US) | 2008-01-24 | — | — | US | disclosed |
| WO-2007103989-A9 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORP (US) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007103389-A9 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | CARGILL INC (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007103389-A2 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | CARGILL, INCORPORATED (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007103989-A2 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION (US) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100095390-A1 | Aldolases, Nucleic Acids Encoding Them and Methods for Making and Using Them | DERA, ALDOA, TKT | LDHA 56/4885SRR 194/4885OR51E2 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.