SCHEMBL28348396

SCHEMBL28348396

COc1ccc(C(I)c2ccc(S(=O)(=O)O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 4/20 0.50
MMP1 P03956 3/20 0.47
MMP13 P45452 3/20 0.47
MMP2 P08253 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
GAA P10253 1/20 0.47
NPC1 O15118 1/20 0.46
PKLR P30613 1/20 0.46
RAB9A P51151 1/20 0.46
F2 P00734 3/20 0.44
PRSS1 P07477 3/20 0.44
PRSS2 P07478 3/20 0.44
PRSS3 P35030 3/20 0.44
ALDH1A1 P00352 2/20 0.44
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL286762 0.85 PKM (0.67) PKMMMP1MMP13MMP2CA1
SCHEMBL10497952 0.83 PKM (0.64) PKMMMP1MMP13MMP2CA1
Water SCHEMBL8627002 0.83 PKM (0.64) PKMMMP1MMP13MMP2CA1
Hydrochloric Acid SCHEMBL1328452 0.83 PKM (0.64) PKMMMP1MMP13MMP2CA1
Fluoride SCHEMBL27786941 0.83 PKM (0.64) PKMMMP1MMP13MMP2CA1
Ammonia Solution, Strong SCHEMBL25386463 0.83 PKM (0.64) PKMMMP1MMP13MMP2CA1
SCHEMBL8627561 0.83 PKM (0.64) PKMMMP1MMP13MMP2CA1
Hydrogen Sulfide SCHEMBL27655402 0.83 PKM (0.64) PKMMMP1MMP13MMP2CA1
SCHEMBL28900059 0.82 MMP2 (0.44) MMP13MMP2CA1CA2MMP9
Nitrogen SCHEMBL28637787 0.81 PKM (0.61) PKMMMP1MMP13MMP2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110577836-A Liquid crystal composition for light conversion element, mixture, polymer/liquid crystal composite material, element, and laser radar 捷恩智株式会社 2019-12-17 CN disclosed