Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 4/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 9/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345080 | 0.87 | LMNA (0.41) | LMNAPOLBGAABACE1BACE2 | |
| SCHEMBL28345182 | 0.87 | ACACB (0.32) | — | |
| SCHEMBL28348087 | 0.86 | LMNA (0.43) | LMNAPOLBGAABACE1BACE2 | |
| SCHEMBL28345167 | 0.86 | LMNA (0.40) | LMNAPOLBGAABACE1BACE2 | |
| SCHEMBL28345531 | 0.83 | LMNA (0.38) | LMNAPOLBGAABACE1BACE2 | |
| SCHEMBL28350649 | 0.80 | LMNA (0.40) | LMNAPOLBGAABACE1BACE2 | |
| SCHEMBL28348147 | 0.80 | LMNA (0.44) | LMNAPOLBGAABACE1BACE2 | |
| SCHEMBL28958595 | 0.78 | LMNA (0.42) | LMNAPOLBGAABACE1BACE2 | |
| SCHEMBL28350304 | 0.78 | LMNA (0.42) | LMNAPOLBGAABACE1BACE2 | |
| SCHEMBL13516088 | 0.78 | LMNA (0.43) | LMNAPOLBGAABACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110615765-B | (1H-pyrazole-4-formamido) ethyl benzoate compound and preparation method and application thereof | 浙江工业大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-110615765-A | (1H-pyrazole-4-formamido) ethyl benzoate compound and preparation method and application thereof | 浙江工业大学 | 2019-12-27 | — | — | CN | disclosed |