Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 10/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28350304 | 1.00 | LMNA (0.42) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28345167 | 0.91 | LMNA (0.40) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28354369 | 0.85 | ACACB (0.33) | — | |
| SCHEMBL28354213 | 0.83 | LMNA (0.45) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28350366 | 0.83 | LMNA (0.45) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28345080 | 0.79 | LMNA (0.41) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28348087 | 0.78 | LMNA (0.43) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28348577 | 0.78 | LMNA (0.41) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28348615 | 0.78 | GAA (0.37) | GAADGAT1 | |
| SCHEMBL28345531 | 0.78 | LMNA (0.38) | LMNAPOLBGAADGAT1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110734403-B | (S) -2- (1H-pyrazole-4-formamido) propyl benzoate compound and preparation method and application thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2021-08-31 | — | — | CN | disclosed |
| CN-110734403-A | (S) -2- (1H-pyrazole-4-formamido) propyl benzoate compound and preparation method and application thereof | 浙江工业大学 | 2020-01-31 | — | — | CN | disclosed |