Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30413179 | 0.85 | KDM4E (0.65) | KDM4EALDH1A1EGLN2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL30411740 | 0.84 | KDM4E (0.63) | KDM4EALDH1A1EGLN2LMNAMAPT | |
| SCHEMBL14804201 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1EGLN2HPGDHSD17B10 | |
| SCHEMBL28348704 | 0.75 | KDM4E (0.65) | KDM4EALDH1A1EGLN2LMNAMAPT | |
| SCHEMBL1938769 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1EGLN2SSTR2EGLN1 | |
| SCHEMBL20522394 | 0.73 | HTR7 (0.58) | KDM4EALDH1A1EGLN2HPGDFEN1 | |
| SCHEMBL3442725 | 0.70 | KDM4E (0.56) | KDM4EALDH1A1EGLN2USP30LMNA | |
| SCHEMBL2072485 | 0.70 | KDM4E (1.00) | KDM4EALDH1A1EGLN2LMNAHPGD | |
| SCHEMBL1939787 | 0.68 | ATR (0.44) | KDM4EALDH1A1SSTR2EGLN1NOTUM | |
| SCHEMBL1939792 | 0.68 | ATR (0.44) | KDM4EALDH1A1SSTR2EGLN1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024352-A | Novel inhibitors | 维沃里翁治疗股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-110719910-B | Novel inhibitors | 维沃里翁治疗股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-110719910-A | Novel inhibitors | 前体生物药物股份公司 | 2020-01-21 | — | — | CN | disclosed |