Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850036 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10EGLN2 | |
| SCHEMBL8569982 | 0.82 | ALDH1A1 (0.73) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL1154557 | 0.81 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL16793536 | 0.81 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL2557573 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL2073370 | 0.79 | GAA (0.74) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL30413179 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10GRM2 | |
| SCHEMBL28348704 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL823501 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10DRD2 | |
| SCHEMBL3076269 | 0.78 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863444-B2 | 4-aminopyrrolopyrimidines as kinase inhibitors | ABBOTT LABORATORIES (US) | 2011-01-04 | — | — | US | disclosed |