Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20996162 | 0.94 | GAA (0.42) | GAAITGB3ITGA2BHDAC6ALDH1A1 | |
| SCHEMBL20996163 | 0.94 | GAA (0.42) | GAAITGB3ITGA2BHDAC6ALDH1A1 | |
| SCHEMBL19463263 | 0.83 | GAA (0.42) | GAAITGB3ITGA2BHDAC6ALDH1A1 | |
| SCHEMBL20371134 | 0.81 | GAA (0.45) | GAAHDAC6ALDH1A1KMT2APDE4B | |
| SCHEMBL28349581 | 0.79 | HDAC6 (0.44) | ITGB3ITGA2BHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL30910298 | 0.79 | HDAC6 (0.44) | ITGB3ITGA2BHDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL31606446 | 0.79 | GAA (0.45) | GAAHDAC6ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL12005099 | 0.78 | PDE4B (0.51) | KMT2ANPSR1PDE4BSLC6A1SLC6A11 | |
| SCHEMBL12004675 | 0.78 | PDE4B (0.51) | KMT2ANPSR1PDE4BSLC6A1SLC6A11 | |
| SCHEMBL12004703 | 0.78 | PDE4B (0.51) | KMT2ANPSR1PDE4BSLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365662-A | Method of treatment | 盖纳万科学有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-110741087-A | Targeted compositions | 阿布特斯生物制药公司 | 2020-01-31 | — | — | CN | disclosed |