Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910298 | 1.00 | HDAC6 (0.44) | HDAC6ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19463709 | 0.93 | HDAC6 (0.43) | HDAC6ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19463708 | 0.93 | HDAC6 (0.43) | HDAC6ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28349578 | 0.87 | MEN1 (0.45) | HDAC6ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24383281 | 0.85 | ALDH1A1 (0.44) | HDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL20149858 | 0.83 | ALDH1A1 (0.46) | HDAC6ALDH1A1 | |
| SCHEMBL31606446 | 0.80 | GAA (0.45) | HDAC6ALDH1A1CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL20371134 | 0.80 | GAA (0.45) | HDAC6ALDH1A1HDAC3HDAC1 | |
| SCHEMBL25598334 | 0.79 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL28349292 | 0.79 | GAA (0.43) | HDAC6ALDH1A1SMN1; SMN2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365662-A | Method of treatment | 盖纳万科学有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-110741087-A | Targeted compositions | 阿布特斯生物制药公司 | 2020-01-31 | — | — | CN | disclosed |