Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20996163 | 0.89 | GAA (0.42) | GAAHDAC6ALDH1A1KMT2ANPSR1 | |
| SCHEMBL20996162 | 0.89 | GAA (0.42) | GAAHDAC6ALDH1A1KMT2ANPSR1 | |
| SCHEMBL28349292 | 0.83 | GAA (0.43) | GAAHDAC6ALDH1A1KMT2ANPSR1 | |
| SCHEMBL19463709 | 0.80 | HDAC6 (0.43) | HDAC6ALDH1A1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL19463708 | 0.80 | HDAC6 (0.43) | HDAC6ALDH1A1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL24383374 | 0.76 | KMT2A (0.43) | HDAC6ALDH1A1KMT2AASAH1SMN1; SMN2 | |
| SCHEMBL31606446 | 0.76 | GAA (0.45) | GAAHDAC6ALDH1A1KMT2AASAH1 | |
| SCHEMBL20799447 | 0.76 | ALDH1A1 (0.50) | ALDH1A1NPSR1SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL20371134 | 0.74 | GAA (0.45) | GAAHDAC6ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL716445 | 0.74 | SLC6A11 (0.43) | HDAC6ALDH1A1KMT2ASMN1; SMN2SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019051257-A2 | METHODS FOR TREATING HEPATITIS B INFECTIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-03-14 | — | — | WO | disclosed |
| EP-3443092-A1 | TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS | Arbutus Biopharma Corporation (CA) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017177326-A1 | TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2017-10-19 | — | — | WO | disclosed |