Urethane

Urethane

SCHEMBL28350198

C=Cc1ccccc1C=C.CCOC(N)=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.54
TSHR P16473 1/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
PLIN1 O60240 1/20 0.43
POLB P06746 1/20 0.43
PLIN5 Q00G26 1/20 0.43
ABHD5 Q8WTS1 1/20 0.43
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP1A2 P05177 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 1/20 0.40
CYP2C19 P33261 1/20 0.40
RAB9A P51151 1/20 0.40
USP2 O75604 1/20 0.40
KDM4E B2RXH2 4/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1256040 0.84 MEN1 (0.53) ALOX15TSHRMEN1KMT2ALMNA
Acrylic Acid Ethyl Ester SCHEMBL10887714 0.82 THRB (0.47) TSHRMEN1KMT2ALMNAMAPT
Styrene SCHEMBL4423746 0.81 MEN1 (0.50) ALOX15TSHRMEN1KMT2ALMNA
Styrene SCHEMBL5865142 0.81 MEN1 (0.50) ALOX15TSHRMEN1KMT2ALMNA
Styrene SCHEMBL11076328 0.80 MEN1 (0.49) ALOX15TSHRMEN1KMT2ALMNA
Styrene SCHEMBL7214028 0.80 MEN1 (0.49) ALOX15TSHRMEN1KMT2ALMNA
SCHEMBL377458 0.79 CYP4F2 (0.55) ALOX15TSHRALDH1A1HSD17B10CYP1A2
SCHEMBL28921993 0.79 MAPT (0.49) TSHRMEN1KMT2ALMNAMAPT
Styrene SCHEMBL28309241 0.79 MEN1 (0.47) ALOX15TSHRMEN1KMT2ALMNA
Naphthalene SCHEMBL9435323 0.79 ALOX15 (0.65) ALOX15TSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724574-A Preparation method of lubricating oil additive with anti-wear and anti-friction effects 马鞍山市三川机械制造有限公司 2020-01-24 CN disclosed