Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551673 | 0.79 | NOTUM (0.50) | ALDH1A1L3MBTL1TDP1NOTUM | |
| SCHEMBL8199590 | 0.73 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1SLC22A12S1PR1DHODH | |
| SCHEMBL6972704 | 0.71 | CFTR (0.41) | ALDH1A1L3MBTL1SLC22A12DHODHCYP11B2 | |
| SCHEMBL15236975 | 0.71 | S1PR1 (0.48) | ALDH1A1L3MBTL1SLC22A12S1PR1CYP11B2 | |
| SCHEMBL6777807 | 0.69 | NOTUM (0.48) | ALDH1A1L3MBTL1SLC22A12S1PR1CYP11B2 | |
| SCHEMBL6973287 | 0.69 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1SLC22A12S1PR1DHODH | |
| SCHEMBL6974393 | 0.69 | CYP3A4 (0.38) | ALDH1A1L3MBTL1SLC22A12DHODHCYP11B2 | |
| SCHEMBL6775894 | 0.68 | S1PR1 (0.40) | ALDH1A1L3MBTL1SLC22A12S1PR1DHODH | |
| SCHEMBL6781723 | 0.68 | S1PR1 (0.43) | ALDH1A1L3MBTL1SLC22A12S1PR1DHODH | |
| SCHEMBL6780744 | 0.68 | S1PR1 (0.62) | ALDH1A1L3MBTL1S1PR1KDM4ES1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713963-B2 | Acylated indanyl amines and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-05-11 | — | — | US | claimed |