Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777807 | 0.78 | NOTUM (0.48) | ALDH1A1L3MBTL1SLC22A12S1PR1CYP11B2 | |
| SCHEMBL6977794 | 0.78 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6974393 | 0.78 | CYP3A4 (0.38) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6965929 | 0.77 | CYP2C19 (0.42) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29286036 | 0.77 | RAB9A (0.56) | ALDH1A1CYP3A4CYP2D6CYP2C19ALOX15 | |
| SCHEMBL30366154 | 0.77 | RAB9A (0.56) | ALDH1A1CYP3A4CYP2D6CYP2C19ALOX15 | |
| SCHEMBL6972704 | 0.74 | CFTR (0.41) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL15236975 | 0.74 | S1PR1 (0.48) | ALDH1A1L3MBTL1SLC22A12S1PR1CYP11B2 | |
| SCHEMBL6976691 | 0.74 | LIMK1 (0.38) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8199590 | 0.73 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140921-B1 | 4-TRIFLUOROMETHYL-3-OXAZOLYLPYRIDINES, METHOD FOR PRODUCING THEM, PRODUCTS CONTAINING THE SAME, AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-04-02 | — | — | EP | disclosed |