Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247193 | 1.00 | MAPT (0.54) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL28404528 | 0.85 | TNFRSF1A (0.53) | MAPTLMNANPC1RAB9ACYP1B1 | |
| SCHEMBL28347942 | 0.85 | MAOB (0.49) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL28413016 | 0.85 | MAOB (0.49) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL28410857 | 0.85 | MAOB (0.50) | MAPTCYP1B1MAOBBCHECYP1A2 | |
| SCHEMBL20746318 | 0.83 | TBXAS1 (0.40) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL20746319 | 0.83 | TBXAS1 (0.40) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL28404409 | 0.82 | CYP2D6 (0.58) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL28351459 | 0.82 | CYP2D6 (0.58) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL28404803 | 0.81 | MAPT (0.52) | MAPTLMNAMAOBHDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110756222-B | Nucleoside triphosphate artificial metalloenzyme and preparation and application thereof | 陕西师范大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-110511259-B | Cyclic dinucleotide artificial metalloenzyme, preparation thereof and application thereof in catalyzing asymmetric Friedel-Crafts reaction | 陕西师范大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-110756222-A | Nucleoside triphosphate artificial metalloenzyme and preparation and application thereof | 陕西师范大学 | 2020-02-07 | — | — | CN | disclosed |