Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | P4HB | P07237 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28413016 | 0.82 | MAOB (0.49) | MAPTALDH1A1LMNAL3MBTL1P4HB | |
| SCHEMBL28410857 | 0.82 | MAOB (0.50) | MAPTALDH1A1GAAMAOBMAOA | |
| SCHEMBL28347942 | 0.82 | MAOB (0.49) | MAPTALDH1A1LMNAL3MBTL1P4HB | |
| SCHEMBL28404528 | 0.82 | TNFRSF1A (0.53) | MAPTALDH1A1LMNAL3MBTL1HTT | |
| SCHEMBL28247193 | 0.81 | MAPT (0.54) | MAPTALDH1A1LMNAHDAC2SMN1; SMN2 | |
| SCHEMBL28351393 | 0.81 | MAPT (0.54) | MAPTALDH1A1LMNAHDAC2SMN1; SMN2 | |
| SCHEMBL20754750 | 0.80 | TBXAS1 (0.38) | MAPTALDH1A1LMNAHDAC2MAOB | |
| SCHEMBL28351459 | 0.80 | CYP2D6 (0.58) | MAPTALDH1A1LMNAL3MBTL1P4HB | |
| SCHEMBL28404409 | 0.80 | CYP2D6 (0.58) | MAPTALDH1A1LMNAL3MBTL1P4HB | |
| SCHEMBL20746319 | 0.77 | TBXAS1 (0.40) | MAPTALDH1A1LMNASMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233843-B | Gamma-butenolide derivative and preparation method and application thereof | 中山大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-111233843-A | Gamma-butenolide derivative and preparation method and application thereof | 中山大学 | 2020-06-05 | — | — | CN | disclosed |