SCHEMBL28351925

SCHEMBL28351925

Brc1csc2cc(-c3ccccc3)ccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 2/20 0.41
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
LIMK1 P53667 1/20 0.39
PIK3CA P42336 1/20 0.39
PI4KA P42356 1/20 0.39
PI4KB Q9UBF8 1/20 0.39
GRIN2D O15399 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
ALOX5 P09917 1/20 0.36
JAK2 O60674 1/20 0.36
F9 P00740 2/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16238206 0.85 ALDH1A1 (0.41) ALDH1A1MAPK1CRHBPCRHR2LIMK1
SCHEMBL20654524 0.79 LIMK1 (0.38) ALDH1A1LIMK1PIK3CAPI4KAPI4KB
SCHEMBL21338369 0.79 TNKS2 (0.44) ALDH1A1LIMK1PIK3CAPI4KAPI4KB
SCHEMBL28348703 0.79 RAB9A (0.36) ALDH1A1MEN1NPC1LMNAMAPT
SCHEMBL28352061 0.76 MCL1 (0.42) KDM4E
SCHEMBL17912642 0.75 CYP2A6 (0.61) ALDH1A1LIMK1PIK3CAPI4KAPI4KB
SCHEMBL21622688 0.74 LIMK1 (0.40) ALDH1A1MAPK1CRHBPCRHR2LIMK1
SCHEMBL28351542 0.74 MAP3K8 (0.39) LIMK1PIK3CAPI4KAPI4KBNPC1
SCHEMBL25232594 0.73 CYP2A6 (0.46) ALDH1A1MAPK1JAK2MAPT
SCHEMBL12562737 0.73 LIMK1 (0.51) ALDH1A1MAPK1LIMK1PIK3CAPI4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734452-A semiconductor materials, and preparation method and application thereof 北京大学深圳研究生院 2020-01-31 CN disclosed