SCHEMBL28352930

SCHEMBL28352930

CC(n1c(=O)[nH]c2ccc(Oc3ccc(F)cc3)cc21)C(C)(C)O

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PGR P06401 7/20 0.51
B3GNT2 Q9NY97 11/20 0.48
MAOB P27338 1/20 0.43
DAO P14920 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28352929 1.00 PGR (0.51) PGRB3GNT2MAOBDAO
SCHEMBL28353164 0.78 B3GNT2 (0.52) B3GNT2MAOB
SCHEMBL28353166 0.78 B3GNT2 (0.52) B3GNT2MAOB
SCHEMBL25432383 0.74 B3GNT2 (0.64) B3GNT2
SCHEMBL29464129 0.70 PGR (0.78) PGRB3GNT2MAOBDAO
SCHEMBL2970468 0.70 PGR (0.78) PGRB3GNT2MAOBDAO
SCHEMBL30930127 0.67 MAOB (0.64) PGRB3GNT2MAOB
SCHEMBL7367213 0.67 MAOB (0.64) PGRB3GNT2MAOB
SCHEMBL25352150 0.67 B3GNT2 (0.47) B3GNT2
SCHEMBL28356392 0.65 MAOB (0.42) PGRB3GNT2MAOBDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110612290-A Novel benzimidazolone compounds and medicinal use thereof 大日本住友制药株式会社 2019-12-24 CN claimed
CN-110612290-A Novel benzimidazolone compounds and medicinal use thereof 大日本住友制药株式会社 2019-12-24 CN disclosed