Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15442018 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EHPGDRAB9A | |
| SCHEMBL4889215 | 0.82 | APP (0.38) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL24106352 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ELMNARAB9A | |
| SCHEMBL11744074 | 0.81 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL28250891 | 0.81 | MAPT (0.40) | MAPTKDM4ERAB9ACYP1A2CES2 | |
| SCHEMBL28356737 | 0.81 | APP (0.38) | ALDH1A1MAPTRAB9ASMN1; SMN2GPBAR1 | |
| SCHEMBL194085 | 0.80 | HTT (0.46) | L3MBTL1KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL969001 | 0.79 | SMN1; SMN2 (0.52) | ALDH1A1L3MBTL1MAPTLMNARAB9A | |
| SCHEMBL15442197 | 0.78 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL28250869 | 0.78 | NR1H4 (0.47) | ALDH1A1LMNARAB9ACYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4553077-A1 | SULFOXIMINE COMPOUND HAVING FGFR INHIBITORY EFFECT, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Kinoteck Therapeutics Co., Ltd (CN) | 2025-05-14 | — | — | EP | disclosed |
| CN-118255706-A | Synthesis method of oxindole compound | 浙江工业大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-106749214-B | Compound containing 1, 3-benzoxazole difluoromethylene indolone and preparation method thereof | 上海大学 | 2020-01-17 | — | — | CN | disclosed |