Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835200 | 0.89 | ALOX15 (0.53) | MAPTLMNAESR1ALOX15PGR | |
| SCHEMBL9169476 | 0.88 | ESR1 (0.53) | MAPTLMNAESR1ALOX15PGR | |
| SCHEMBL6463142 | 0.85 | ESR1 (0.55) | MAPTLMNAESR1ALOX15PGR | |
| SCHEMBL9558275 | 0.81 | ESR1 (0.58) | MAPTLMNAESR1ALOX15PGR | |
| SCHEMBL3451745 | 0.81 | ESR1 (0.58) | MAPTLMNAESR1ALOX15PGR | |
| SCHEMBL2832705 | 0.80 | CYP19A1 (0.38) | MAPTLMNAESR1PGRCYP3A4 | |
| SCHEMBL2834607 | 0.78 | ESR1 (0.50) | MAPTLMNAESR1ALOX15PGR | |
| SCHEMBL7616946 | 0.78 | LMNA (0.35) | MAPTLMNAESR1ALOX15PGR | |
| SCHEMBL5146812 | 0.76 | CYP19A1 (0.35) | MAPTLMNAESR1ALOX15PGR | |
| SCHEMBL2831316 | 0.76 | ESR1 (0.47) | MAPTLMNAESR1ALOX15PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437156-B1 | ANTIANXIETY; AFFECTS THE FUNCTION OF THE AUTONOMIC NERVOUS SYSTEM AND A VARIETY OF BEHAVIORAL OR PHYSIOLOGICAL ACTIONS; VOMEROPHERINS; PHEROMONES | PHERIN CORPORATION | 2002-08-20 | — | — | US | claimed |
| US-20100111896-A1 | Items Containing A Human Pheromone Component | MARENBERG BARRY J | 2010-05-06 | — | — | US | disclosed |
| WO-2007062023-A2 | ITEMS CONTAINING A HUMAN PHEROMONE COMPONENT | BRAGINSKY PHILIP Y (US) | 2007-05-31 | — | — | WO | disclosed |