Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12755278 | 0.86 | KDM4E (0.40) | KDM4EHPGDALDH1A1POLBTUBB4A | |
| SCHEMBL25338522 | 0.80 | ALDH1A1 (0.44) | KDM4EHPGDALDH1A1PIM1MEN1 | |
| SCHEMBL28356984 | 0.79 | SLC6A4 (0.43) | KDM4ELMNAMAPTENPP3ENPP1 | |
| SCHEMBL7004139 | 0.77 | KDM4E (0.42) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL28356987 | 0.76 | KDM4E (0.37) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL28356918 | 0.73 | KDM4E (0.40) | KDM4EHPGDALDH1A1KMT2APOLB | |
| SCHEMBL29763553 | 0.73 | KDM4E (0.40) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL12755300 | 0.73 | KDM4E (0.40) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL28356858 | 0.73 | KDM4E (0.40) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL12755285 | 0.71 | KDM4E (0.51) | KDM4EHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-A | α unsaturated amide compound | 协和麒麟株式会社 | 2020-02-07 | — | — | CN | disclosed |