Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NQO2 | P16083 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12755300 | 1.00 | KDM4E (0.40) | KDM4EHPGDNQO2ALDH1A1MEN1 | |
| SCHEMBL12755278 | 0.87 | KDM4E (0.40) | KDM4EHPGDNQO2ALDH1A1POLB | |
| SCHEMBL12755285 | 0.86 | KDM4E (0.51) | KDM4EHPGDNQO2ALDH1A1MEN1 | |
| SCHEMBL15450918 | 0.81 | KDM4E (0.42) | KDM4EHPGDNQO2ALDH1A1MEN1 | |
| SCHEMBL12829337 | 0.81 | HPGD (0.43) | KDM4EHPGDNQO2ALDH1A1MEN1 | |
| SCHEMBL29763525 | 0.74 | HPGD (0.35) | KDM4EHPGDNQO2ALDH1A1CYP19A1 | |
| SCHEMBL28426043 | 0.73 | ERN1 (0.47) | KDM4EHPGDNQO2ALDH1A1MEN1 | |
| SCHEMBL28353145 | 0.73 | KDM4E (0.39) | KDM4EHPGDNQO2ALDH1A1MEN1 | |
| SCHEMBL830967 | 0.73 | ALDH1A1 (0.43) | KDM4EHPGDNQO2ALDH1A1KMT2A | |
| SCHEMBL12755274 | 0.70 | ITK (0.45) | KDM4EHPGDNQO2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288424-A1 | NOVEL HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167631-A1 | NOVEL HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-08-11 | — | — | WO | disclosed |