Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958657 | 0.83 | PARP1 (0.42) | MAPTPARP1HTTKMT2AMEN1 | |
| SCHEMBL3921082 | 0.76 | MAPT (0.58) | MAPTNPSR1XBP1HTTKMT2A | |
| SCHEMBL18935911 | 0.70 | MAPT (0.53) | MAPTNPSR1XBP1PARP1HTT | |
| SCHEMBL28353425 | 0.70 | SLC6A4 (0.45) | MAPTNPSR1RAB9AKDM4EBRD4 | |
| SCHEMBL19472054 | 0.70 | MAPT (0.50) | MAPTNPSR1XBP1HTTKMT2A | |
| SCHEMBL14696066 | 0.69 | GPR35 (0.56) | MAPTNPSR1XBP1KMT2AMEN1 | |
| SCHEMBL22438868 | 0.68 | MAPT (0.45) | MAPTNPSR1XBP1HTTKMT2A | |
| SCHEMBL3485581 | 0.68 | SRPK1 (0.60) | MAPTNPSR1XBP1HTTKMT2A | |
| SCHEMBL3919080 | 0.68 | GAA (0.59) | MAPTPARP1HTTKMT2AMEN1 | |
| SCHEMBL20554412 | 0.68 | KMT2A (0.60) | MAPTNPSR1XBP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-110770211-A | α unsaturated amide compound | 协和麒麟株式会社 | 2020-02-07 | — | — | CN | disclosed |