Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28353161 | 0.83 | MAPT (0.49) | PARP1RXFP1PTGS1KDM4EKMT2A | |
| SCHEMBL29259242 | 0.81 | DHODH (0.43) | TAS2R14MAPK1 | |
| SCHEMBL29259243 | 0.73 | TOP2A (0.37) | MAPTCYP2D6 | |
| SCHEMBL29259245 | 0.72 | AR (0.43) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL28352950 | 0.72 | AR (0.43) | MAPTRAB9ALMNA | |
| SCHEMBL2130562 | 0.72 | TRPV1 (0.58) | PTGS1KMT2ATRPV1MAPTMEN1 | |
| SCHEMBL28352964 | 0.71 | DAO (0.43) | MAPT | |
| SCHEMBL28356859 | 0.71 | NQO2 (0.39) | PTGS1TRPV1MAPT | |
| SCHEMBL22439110 | 0.70 | PTGS1 (0.40) | RXFP1PTGS1KDM4EKMT2AHTT | |
| SCHEMBL20554224 | 0.70 | ELANE (0.53) | PTGS1KMT2ATRPV1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-110770211-A | α unsaturated amide compound | 协和麒麟株式会社 | 2020-02-07 | — | — | CN | disclosed |