Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 15/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.47 |
| ▸ | LIPE | Q05469 | 2/20 | 0.43 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352782 | 0.84 | SCN9A (0.38) | SCN9ASCN10A | |
| SCHEMBL28352781 | 0.82 | SCN9A (0.50) | SCN9ASCN10ALIPE | |
| SCHEMBL24117147 | 0.81 | SCN9A (0.48) | SCN9ASCN10ASCN7AKCNH2MAPK1 | |
| SCHEMBL28356812 | 0.80 | TRPC5 (0.39) | LIPEKCNH2 | |
| SCHEMBL28356584 | 0.79 | TRIM24 (0.38) | — | |
| SCHEMBL18730390 | 0.78 | SCN9A (0.55) | SCN9ASCN10ASCN7AKCNH2 | |
| SCHEMBL29463824 | 0.78 | SCN9A (0.55) | SCN9ASCN10ASCN7AKCNH2 | |
| SCHEMBL28352567 | 0.77 | MEN1 (0.41) | — | |
| SCHEMBL24117152 | 0.76 | PARG (0.41) | LIPEKCNH2 | |
| SCHEMBL28356469 | 0.71 | MAPK1 (0.47) | SCN9ASCN10AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612290-A | Novel benzimidazolone compounds and medicinal use thereof | 大日本住友制药株式会社 | 2019-12-24 | — | — | CN | claimed |
| CN-110612290-A | Novel benzimidazolone compounds and medicinal use thereof | 大日本住友制药株式会社 | 2019-12-24 | — | — | CN | disclosed |