Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870322 | 0.87 | PDE4B (0.49) | PDE4BTDP1L3MBTL1MAPTKDM4E | |
| SCHEMBL15574252 | 0.76 | HSD17B2 (0.62) | HSD17B2MAPTKDM4EGAANPC1 | |
| SCHEMBL6867384 | 0.76 | TDP1 (0.64) | TDP1L3MBTL1MAPTGAALMNA | |
| SCHEMBL25287265 | 0.75 | HSD17B2 (0.50) | TDP1L3MBTL1HSD17B2KDM4ELMNA | |
| SCHEMBL25248481 | 0.75 | HSD17B2 (0.50) | TDP1L3MBTL1HSD17B2KDM4ELMNA | |
| SCHEMBL13529210 | 0.75 | CA12 (0.62) | TDP1L3MBTL1HSD17B2KDM4EGAA | |
| SCHEMBL13529212 | 0.74 | HSD17B2 (0.52) | TDP1L3MBTL1HSD17B2MAPTKDM4E | |
| SCHEMBL13529209 | 0.74 | HSD17B2 (0.52) | TDP1L3MBTL1HSD17B2MAPTKDM4E | |
| SCHEMBL300248 | 0.73 | HSD17B2 (0.54) | TDP1L3MBTL1HSD17B2NPC1RAB9A | |
| SCHEMBL3196742 | 0.73 | KCNH2 (0.64) | TDP1L3MBTL1MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406451-B | Pyrrolopyrimidines and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | 福马治疗股份有限公司 | 2019-12-17 | — | — | CN | disclosed |